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Curriculum
Activity Information
Target Audience
Learning Objectives
Technical Requirements
The Curriculum in Iron Metabolism & Related Disorders is supported by an educational grant from
Projects In Knowledge is a registered trademark of Projects In Knowledge, Inc.
Course materials have been developed for use outside of the United States.
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Epidemiology and Disease Pathophysiology: Myelodysplastic Syndromes
"Myelodysplastic Syndromes: Review of Pathophysiology and Current Novel Treatment Approaches," by E.D. Warlick and B.D. Smith, Current Cancer Drug Targets. 2007: 7: 541-558, is reprinted here with permission. We wish to thank authors E.D. Warlick and B.D. Smith and Bentham Science Publishers, Ltd, publisher of Current Cancer Drug Targets.
Table of Contents
| Topic |
Page |
| 1. Introduction |
541 |
| 2. Classification Systems |
541 |
| 3. Theories in MDS Pathophysiology |
542 |
| 4. Standard Treatment for MDS |
548 |
| 5. New Therapeutic Approaches Under Development for MDS |
551 |
| 6. Summary |
553 |
| References |
554 |
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Target Audience
This activity is designed for haematologists, medical oncologists, haematology-oncology specialists, and other healthcare professionals involved in the screening, evaluation, treatment, and management of adults and children with iron overload, resulting from the spectrum of chronic iron overload diseases. |
Learning Objectives
After participating in this activity, participants should be better able to:
- Analyze the current classification systems for MDS to accurately classify your MDS patients in order to determine prognosis and to choose the most effective treatment strategies.
- Assess the complexity of the pathophysiologic steps that can lead to the development of MDS for optimal treatment selection that improve patient outcomes.
- Utilize an understanding of the mechanisms of action, efficacy, and safety of currently available agents for the treatment of MDS, to formulate treatment strategies most likely to improve clinical outcomes.
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