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The Curriculum in Iron Metabolism & Related Disorders is supported by an educational grant from
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Iron Overload Case Library II, Case 3: The Role of Iron Chelation in High-Risk Myelodysplastic Syndromes Before Allogeneic Haematopoietic Stem Cell Transplant


Iron overload is often present in patients with myelodysplastic syndromes preparing to undergo haematopoietic stem cell transplantation due to frequent red blood cell transfusion. Pretransplant serum ferritin levels are strongly associated with posttransplant outcomes, including overall survival. In this case study, Dr. Aristoteles Giagounidis presents the case of a transfusion-dependent woman about to undergo transplant, attending to her myelodysplastic disease as well as iron parameters.
Faculty
Aristoteles A.N. Giagounidis, MD, PhD
Aristoteles A.N. Giagounidis, MD, PhD
Head of Clinical Research Unit
Department of Haematology and Oncology
St. Johannes Hospital
Duisburg, Germany

Target Audience

This activity is designed for haematologists, medical oncologists, haematology-oncology specialists, and other healthcare professionals involved in the screening, evaluation, treatment, and management of adults and children with iron overload, resulting from the spectrum of chronic iron overload diseases.

Learning Objectives


After participating in this activity, participants should be better able to:
  • Evaluate the role of iron chelation in high-risk myelodysplastic syndromes prior to allogeneic haematopoietic stem cell transplant.
Disclosure Information

Aristoteles A.N. Giagounidis, MD, PhD, is on the speakers bureau of Celgene Corporation; is on advisory boards for Novartis Pharmaceuticals Corporation and Pharmion Corporation; and is a stock shareholder in Hoffmann-La Roche Inc.

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