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Nonresponders to Iron Chelation Therapy


Non-response to chelation therapy can be a result of a variety of factors, each presenting particular management challenges. Join Dr. John B. Porter of the University College London and Dr. Kai-Hsin Lin of National Taiwan University Hospital as they discuss the different measurements used to determine non-response, reasons for non-response, variations in the rates of non-response to different chelators, and how best to improve response rates in patients with sub-optimal iron balance. Case presentations describing the management of two very different non-responders from actual practice provide hands-on examples of how to overcome some of these challenges.
Faculty
Kai-Hsin Lin, MD
Kai-Hsin Lin, MD
Professor of Paediatrics
National Taiwan
  University Hospital
Taipei, Taiwan
John B. Porter, MA, MD, FRCP
John B. Porter, MA, MD, FRCP
Professor, Department of
  Haematology
University College
  London
London, United Kingdom

Target Audience

This activity is designed for haematologists, medical oncologists, haematology-oncology specialists, and other healthcare professionals involved in the screening, evaluation, treatment, and management of adults and children with iron overload, resulting from the spectrum of chronic iron overload diseases.

Learning Objectives


After participating in this activity, participants should be better able to:
  • Evaluate the reasons for patient non-response to chelation therapy in order to determine how best to improve response rates in patients with sub-optimal iron balance.
Disclosure Information

Kai-Hsin Lin, MD, has disclosed no significant relationships.

John B. Porter, MA, MD, FRCP, has received grant/research support from and is on the speakers bureau of Novartis Pharmaceuticals Corporation; and is a consultant for Genzyme Corporation, Resonance Health Ltd, and Novartis Pharmaceuticals Corporation.

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