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Series of 10 Reports from the 50th American Society of Hematology (ASH) Annual Meeting and Exposition in San Francisco, California 2008
At the 2008 Annual Meeting of ASH, new data from a number of studies were presented on the benefits of iron chelation, particularly in preventing/reversing myocardial iron overload. These reports discuss the recent clinical trial results, focusing on the impact of different regimens of deferasirox, deferiprone, and desferrioxamine on cardiac iron accumulation in patients with a variety of transfusion-dependent anemias, as well as the efficacy of treatment with iron chelators in reversing/ preventing subclinical hypothyroidism. Iron overload as an independent prognostic factor of survival and the evolution to AML in patients with MDS is also discussed.
Target AudienceThis activity is designed for haematologists, medical oncologists, haematology-oncology specialists, and other healthcare professionals involved in the screening, evaluation, treatment, and management of adults and children with iron overload, resulting from the spectrum of chronic iron overload diseases.
- Evaluate results from recent clinical trials of deferasirox, deferiprone, and deferrioxamine in order to choose the most effective chelation regimen to reduce/prevent cardiac iron accumulation in your individual patients with transfusion-dependent anemias.
- Compare dosing schedule and route of administration of available iron chelators in determining treatment that facilitates compliance and increases quality of life of your patients with transfusion-dependent anemias.
- Apply your knowledge of iron overload as a prognostic factor in survival and evolution to AML in patients with MDS in order to determine when and in whom to institute iron chelation therapy.
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