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The Impact of Iron Overload on Survival in MDS Patients
As a result of transfusions used to manage the anaemia of myelodysplastic syndromes, patients often acquire significant iron overload. In turn, both iron overload and transfusion dependence result in decreased survival and quality of life. Join Dr. Aristoteles Giagounidis as he discusses the newest prognostic scoring systems for determining patient survival and progression to acute myeloid anaemia, the impact of iron overload on survival, and the benefits of iron chelation in reducing iron overload, improving haematologic response, and reducing the need for transfusions in these patients.
- Based on the available myelodysplastic syndromes (MDS) prognostic scoring systems, assess the probable median survival and progression to acute myeloid leukaemia of your patients in order to determine optimum patient management and improve outcomes.
- Using MRI, evaluate liver iron concentrations annually in MDS patients receiving regular transfusions in order to initiate iron chelation therapy as soon as there is evidence of iron overload.
||Aristoteles A.N. Giagounidis, MD, PhD
Head, Department of Hematology and Oncology
|Aristoteles A.N. Giagounidis, MD, PhD
is on the speakers bureau of Celgene Corporation; is on advisory boards for Novartis Pharmaceuticals Corporation and Pharmion Corporation; and is a stock shareholder in Hoffmann-La Roche Inc.
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